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Polygenic disruption of retinoid signalling in schizophrenia and a severe cognitive deficit subtype
Retinoid metabolites of vitamin A are intrinsically linked to neural development, connectivity and plasticity, and have been implicated in the pathophysiology of schizophrenia. We hypothesised that a greater burden of common and rare genomic variation in genes involved with retinoid biogenesis and s...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156344/ https://www.ncbi.nlm.nih.gov/pubmed/30532020 http://dx.doi.org/10.1038/s41380-018-0305-0 |