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Alarmin-painted exosomes elicit persistent antitumor immunity in large established tumors in mice

Treating large established tumors is challenging for dendritic cell (DC)-based immunotherapy. DC activation with tumor cell-derived exosomes (TEXs) carrying multiple tumor-associated antigen can enhance tumor recognition. Adding a potent adjuvant, high mobility group nucleosome-binding protein 1 (HM...

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Detalles Bibliográficos
Autores principales: Zuo, Bingfeng, Qi, Han, Lu, Zhen, Chen, Lu, Sun, Bo, Yang, Rong, Zhang, Yang, Liu, Zhili, Gao, Xianjun, You, Abin, Wu, Li, Jing, Renwei, Zhou, Qibing, Yin, HaiFang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156382/
https://www.ncbi.nlm.nih.gov/pubmed/32286296
http://dx.doi.org/10.1038/s41467-020-15569-2