Cargando…
A case of malignant hyperlactaemic acidosis appearing upon treatment with the mono-carboxylase transporter 1 inhibitor AZD3965
A 47-year-old man with metastatic melanoma presented with refractory hyperlactaemic acidosis following the first dose of the mono-carboxylase transporter 1 inhibitor AZD3965 within a “first time in man” clinical trial. The mechanism of the agent and the temporal relationship suggested that this even...
Autores principales: | McNeillis, Rosie, Greystoke, Alastair, Walton, Jon, Bacon, Chris, Keun, Hector, Siskos, Alexandros, Petrides, George, Leech, Nicola, Jenkinson, Fiona, Bowron, Ann, Halford, Sarah, Plummer, Ruth |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156442/ https://www.ncbi.nlm.nih.gov/pubmed/32076124 http://dx.doi.org/10.1038/s41416-020-0727-8 |
Ejemplares similares
-
Correction: A case of malignant hyperlactaemic acidosis appearing upon treatment with the mono-carboxylase transporter 1 inhibitor AZD3965
por: McNeillis, Rosie, et al.
Publicado: (2020) -
In Vivo Anticancer Activity of AZD3965: A Systematic Review
por: Silva, Ana, et al.
Publicado: (2021) -
Tracing Nutrient Flux Following Monocarboxylate Transporter-1 Inhibition with AZD3965
por: Braga, Marta, et al.
Publicado: (2020) -
Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma
por: Noble, Richard A., et al.
Publicado: (2017) -
Monocarboxylate transporter 1 blockade with AZD3965 inhibits lipid biosynthesis and increases tumour immune cell infiltration
por: Beloueche-Babari, Mounia, et al.
Publicado: (2020)