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Glycolytic reprograming in Salmonella counters NOX2-mediated dissipation of ΔpH

The microbial adaptations to the respiratory burst remain poorly understood, and establishing how the NADPH oxidase (NOX2) kills microbes has proven elusive. Here we demonstrate that NOX2 collapses the ΔpH of intracellular Salmonella Typhimurium. The depolarization experienced by Salmonella undergoi...

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Detalles Bibliográficos
Autores principales: Chakraborty, Sangeeta, Liu, Lin, Fitzsimmons, Liam, Porwollik, Steffen, Kim, Ju-Sim, Desai, Prerak, McClelland, Michael, Vazquez-Torres, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156505/
https://www.ncbi.nlm.nih.gov/pubmed/32286292
http://dx.doi.org/10.1038/s41467-020-15604-2

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