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Targeting Rac and Cdc42 GEFs in Metastatic Cancer

The Rho family GTPases Rho, Rac, and Cdc42 have emerged as key players in cancer metastasis, due to their essential roles in regulating cell division and actin cytoskeletal rearrangements; and thus, cell growth, migration/invasion, polarity, and adhesion. This review will focus on the close homologs...

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Detalles Bibliográficos
Autores principales:	Maldonado, Maria del Mar, Medina, Julia Isabel, Velazquez, Luis, Dharmawardhane, Suranganie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156542/ https://www.ncbi.nlm.nih.gov/pubmed/32322580 http://dx.doi.org/10.3389/fcell.2020.00201

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