Obesity-induced overexpression of miR-802 impairs insulin transcription and secretion

B cell dysfunction due to obesity can be associated with alterations in the levels of micro-RNAs (miRNAs). However, the role of miRNAs in these processes remains elusive. Here, we show that miR-802 is increased in the pancreatic islets of obese mouse models and demonstrate that inducible transgenic...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Fangfang, Ma, Dongshen, Zhao, Wanli, Wang, Danwei, Liu, Tingsheng, Liu, Yuhong, Yang, Yue, Liu, Yue, Mu, Jinming, Li, Bingbing, Zhang, Yanfeng, Pan, Yi, Guo, Changying, Du, Hong, Li, Ling, Fu, Xianghui, Cao, Zhengyu, Jin, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156651/
https://www.ncbi.nlm.nih.gov/pubmed/32286278
http://dx.doi.org/10.1038/s41467-020-15529-w

Ejemplares similares

Ejemplares similares