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Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC

Protein ubiquitination is one of the most prevalent post-translational modifications, controlling virtually every process in eukaryotic cells. Recently, the Legionella effector MavC was found to mediate a unique ubiquitination through transglutamination, linking ubiquitin (Ub) to UBE2N through Ub(Gl...

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Detalles Bibliográficos
Autores principales: Mu, Yajuan, Wang, Yue, Huang, Yanfei, Li, Dong, Han, Youyou, Chang, Min, Fu, Jiaqi, Xie, Yongchao, Ren, Jie, Wang, Hao, Zhang, Yi, Luo, Zhao-Qing, Feng, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156659/
https://www.ncbi.nlm.nih.gov/pubmed/32286321
http://dx.doi.org/10.1038/s41467-020-15645-7