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A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence

BACKGROUND: Genome-wide association studies (GWASs) have enriched the fields of genomics and drug development. Adrenocortical carcinoma (ACC) is a rare cancer with a bimodal age distribution and inadequate treatment options. Paediatric ACC is frequently associated with TP53 mutations, with particula...

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Detalles Bibliográficos
Autores principales:	Surakhy, Mirvat, Wallace, Marsha, Bond, Elisabeth, Grochola, Lukasz Filip, Perez, Husein, Di Giovannantonio, Matteo, Zhang, Ping, Malkin, David, Carter, Hannah, Parise, Ivy Zortea S., Zambetti, Gerard, Komechen, Heloisa, Paraizo, Mariana M., Pagadala, Meghana S., Pinto, Emilia M., Lalli, Enzo, Figueiredo, Bonald C., Bond, Gareth L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156685/ https://www.ncbi.nlm.nih.gov/pubmed/32147670 http://dx.doi.org/10.1038/s41416-020-0764-3

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