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Soyasapogenol-A targets CARF and results in suppression of tumor growth and metastasis in p53 compromised cancer cells

We screened some phytochemicals for cytotoxic activity to human cancer cells and identified Soyasapogenol-A (Snol-A) as a potent candidate anti-cancer compound. Interestingly, Soyasapogenin-I (Snin-I) was ineffective. Viability assays endorsed toxicity of Snol-A to a wide variety of cancer cells. Of...

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Detalles Bibliográficos
Autores principales:	Omar, Amr, Kalra, Rajkumar Singh, Putri, Jayarani, Elwakeel, Ahmed, Kaul, Sunil C., Wadhwa, Renu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156697/ https://www.ncbi.nlm.nih.gov/pubmed/32286347 http://dx.doi.org/10.1038/s41598-020-62953-5

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