Molecular mechanism of nur77 gene expression and downstream target genes in the early stage of forskolin-induced differentiation in PC12 cells

Forskolin promotes neuronal differentiation of PC12 cells via the PKA-CREB-dependent signaling pathway. Activation of PKA by forskolin phosphorylates CREB, which then binds to CRE sites in numerous gene promoters. However, it is unclear which gene contains the CRE sites responsible for forskolin-ind...

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Detalles Bibliográficos
Autores principales: Maruoka, Hiroki, Yamazoe, Ryosuke, Takahashi, Ryota, Yatsuo, Keisuke, Ido, Daiki, Fuchigami, Yuki, Hoshikawa, Fumiya, Shimoke, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156746/
https://www.ncbi.nlm.nih.gov/pubmed/32286359
http://dx.doi.org/10.1038/s41598-020-62968-y

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