Using next‐generation sequencing to redefine BRCAness in triple‐negative breast cancer

BRCAness is considered a predictive biomarker to platinum and poly(ADP‐ribose) polymerase (PARP) inhibitors. However, recent trials showed that its predictive value was limited in triple‐negative breast cancer (TNBC) treated with platinum. Moreover, tumors with mutations of DNA damage response (DDR)...

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Detalles Bibliográficos
Autores principales: Lin, Po‐Han, Chen, Ming, Tsai, Li‐Wei, Lo, Chiao, Yen, Tzu‐Chun, Huang, Thomas Yoyan, Chen, Chih‐Kai, Fan, Sheng‐Chih, Kuo, Sung‐Hsin, Huang, Chiun‐Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156820/
https://www.ncbi.nlm.nih.gov/pubmed/31958182
http://dx.doi.org/10.1111/cas.14313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156820/
https://www.ncbi.nlm.nih.gov/pubmed/31958182
http://dx.doi.org/10.1111/cas.14313

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