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Suppression of KIF3A inhibits triple negative breast cancer growth and metastasis by repressing Rb‐E2F signaling and epithelial‐mesenchymal transition

Triple negative breast cancer (TNBC) displays higher heterogeneity, stronger invasiveness, higher risk of metastasis and poorer prognosis compared with major breast cancer subtypes. KIF3A, a member of the kinesin family of motor proteins, serves as a microtubule‐directed motor subunit and has been f...

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Detalles Bibliográficos
Autores principales: Wang, Weilin, Zhang, Runze, Wang, Xiao, Wang, Ning, Zhao, Jing, Wei, Zhimin, Xiang, Fenggang, Wang, Chengqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156822/
https://www.ncbi.nlm.nih.gov/pubmed/32011034
http://dx.doi.org/10.1111/cas.14324

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