Cargando…

Suppression of KIF3A inhibits triple negative breast cancer growth and metastasis by repressing Rb‐E2F signaling and epithelial‐mesenchymal transition

Triple negative breast cancer (TNBC) displays higher heterogeneity, stronger invasiveness, higher risk of metastasis and poorer prognosis compared with major breast cancer subtypes. KIF3A, a member of the kinesin family of motor proteins, serves as a microtubule‐directed motor subunit and has been f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Weilin, Zhang, Runze, Wang, Xiao, Wang, Ning, Zhao, Jing, Wei, Zhimin, Xiang, Fenggang, Wang, Chengqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156822/ https://www.ncbi.nlm.nih.gov/pubmed/32011034 http://dx.doi.org/10.1111/cas.14324

Ejemplares similares

Silencing of KIF3B Suppresses Breast Cancer Progression by Regulating EMT and Wnt/β-Catenin Signaling
por: Wang, Chengqin, et al.
Publicado: (2021)

Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT
por: Zheng, Yan, et al.
Publicado: (2022)

A Six-Epithelial–Mesenchymal Transition Gene Signature May Predict Metastasis of Triple-Negative Breast Cancer
por: Wei, Li Yuan, et al.
Publicado: (2020)

DACH1 inhibits SNAI1-mediated epithelial–mesenchymal transition and represses breast carcinoma metastasis
por: Zhao, F, et al.
Publicado: (2015)

Huaier polysaccharides suppress triple-negative breast cancer metastasis and epithelial-mesenchymal transition by inducing autophagic degradation of Snail
por: Tian, Yuan, et al.
Publicado: (2021)

Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition
por: Garcia, Elizabeth, et al.
Publicado: (2021)

miR-30a inhibits epithelial-mesenchymal transition and metastasis in triple-negative breast cancer by targeting ROR1
por: Wang, Xin, et al.
Publicado: (2018)

MiR-1976 knockdown promotes epithelial–mesenchymal transition and cancer stem cell properties inducing triple-negative breast cancer metastasis
por: Wang, Jingyi, et al.
Publicado: (2020)

Epithelial-mesenchymal transition in breast cancer progression and metastasis
por: Wang, Yifan, et al.
Publicado: (2011)

PRAME promotes epithelial-to-mesenchymal transition in triple negative breast cancer
por: Al-Khadairi, Ghaneya, et al.
Publicado: (2019)

Intercellular Communication Reveals Therapeutic Potential of Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer
por: Liu, Yang, et al.
Publicado: (2022)

Escin Ia suppresses the metastasis of triple-negative breast cancer by inhibiting epithelial-mesenchymal transition via down-regulating LOXL2 expression
por: Wang, Yuhui, et al.
Publicado: (2016)

Epithelial–mesenchymal transition in tumor metastasis
por: Yeung, Kay T., et al.
Publicado: (2016)

NEDD9 may regulate hepatocellular carcinoma cell metastasis by promoting epithelial-mesenchymal-transition and stemness via repressing Smad7
por: Wang, Zhipeng, et al.
Publicado: (2016)

The Response of Triple-Negative Breast Cancer to Neoadjuvant Chemotherapy and the Epithelial–Mesenchymal Transition
por: Zapperi, Stefano, et al.
Publicado: (2023)

The ELF3 transcription factor is associated with an epithelial phenotype and represses epithelial-mesenchymal transition
por: Subbalakshmi, Ayalur Raghu, et al.
Publicado: (2023)

Exposing the Underlying Relationship of Cancer Metastasis to Metabolism and Epithelial-Mesenchymal Transitions
por: Kang, Xin, et al.
Publicado: (2019)

The Function of SARI in Modulating Epithelial-Mesenchymal Transition and Lung Adenocarcinoma Metastasis
por: Wang, Changli, et al.
Publicado: (2012)

MSI2 knockdown represses extrahepatic cholangiocarcinoma growth and invasion by inhibiting epithelial–mesenchymal transition
por: Hu, Feihu, et al.
Publicado: (2018)

Metabolic reprogram associated with epithelial-mesenchymal transition in tumor progression and metastasis
por: Wang, Yifan, et al.
Publicado: (2019)

Down regulated oncogene KIF2C inhibits growth, invasion, and metastasis of hepatocellular carcinoma through the Ras/MAPK signaling pathway and epithelial-to-mesenchymal transition
por: Mo, Shutian, et al.
Publicado: (2022)

Novel Diphenylamine Analogs Induce Mesenchymal to Epithelial Transition in Triple Negative Breast Cancer
por: Bhatt, Akshita B., et al.
Publicado: (2019)

Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple‐negative breast cancer
por: Yamamoto, Mizuki, et al.
Publicado: (2017)

Classification of triple negative breast cancer by epithelial mesenchymal transition and the tumor immune microenvironment
por: Font-Clos, Francesc, et al.
Publicado: (2022)

β-Patchoulene represses hypoxia-induced proliferation and epithelial-mesenchymal transition of liver cancer cells
por: Tu, Huahua, et al.
Publicado: (2022)

HOXD9 promote epithelial‐mesenchymal transition and metastasis in colorectal carcinoma
por: Liu, Mengwei, et al.
Publicado: (2020)

Tamoxifen reverses epithelial–mesenchymal transition by demethylating miR-200c in triple-negative breast cancer cells
por: Wang, Qian, et al.
Publicado: (2017)

Curcumol enhances the anti-tumor effects of metformin via suppressing epithelial-mesenchymal transition in triple-negative breast cancer
por: Wang, Gangyue, et al.
Publicado: (2020)

miR‐655 suppresses epithelial‐to‐mesenchymal transition by targeting Prrx1 in triple‐negative breast cancer
por: Lv, Zhi‐Dong, et al.
Publicado: (2016)

Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis
por: Chien, Ming-Hsien, et al.
Publicado: (2019)

NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling
por: Zhang, Jianchao, et al.
Publicado: (2016)

Long non‐coding RNA ZEB2‐AS1 promotes the proliferation, metastasis and epithelial mesenchymal transition in triple‐negative breast cancer by epigenetically activating ZEB2
por: Zhang, Guoxin, et al.
Publicado: (2019)

MicroRNA-140 Inhibits the Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer
por: Li, Jiazhi, et al.
Publicado: (2018)

PBX3 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition
por: Wang, Shuanhu, et al.
Publicado: (2016)

PARK2 negatively regulates the metastasis and epithelial-mesenchymal transition of glioblastoma cells via ZEB1
por: Wang, Haiyang, et al.
Publicado: (2017)

Contribution of epithelial-mesenchymal transitions to organogenesis and cancer metastasis
por: Campbell, Kyra
Publicado: (2018)

Epithelial-to-Mesenchymal Transition in Metastasis: Focus on Laryngeal Carcinoma
por: Goulioumis, Anastasios, et al.
Publicado: (2022)

ESR2 Drives Mesenchymal-to-Epithelial Transition in Triple-Negative Breast Cancer and Tumorigenesis In Vivo
por: Piperigkou, Zoi, et al.
Publicado: (2022)

CircSTK3 drives the metastasis of colorectal cancer by regulating epithelial-mesenchymal transition
por: Fan, Boyang, et al.
Publicado: (2023)

CEACAM6 is associated with osteosarcoma metastasis and facilitates epithelial–mesenchymal transition in osteosarcoma cells
por: Wang, Zeyu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qn9l1ottosnqpnqmhg39n879lb