Liposomal simvastatin sensitizes C26 murine colon carcinoma to the antitumor effects of liposomal 5‐fluorouracil in vivo

5‐Fluorouracil‐based therapy remains the main approach in colorectal cancer, even though there are still some drawbacks, such as chemoresistance. In this study we combined 5‐fluorouracil encapsulated in long‐circulating liposomes with simvastatin, also encapsulated in long‐circulating liposomes, tha...

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Detalles Bibliográficos
Autores principales: Luput, Lavinia, Sesarman, Alina, Porfire, Alina, Achim, Marcela, Muntean, Dana, Casian, Tibor, Patras, Laura, Rauca, Valentin Florian, Drotar, Denise Minerva, Stejerean, Ioana, Tomuta, Ioan, Vlase, Laurian, Dragos, Nicolae, Toma, Vlad Alexandru, Licarete, Emilia, Banciu, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156830/
https://www.ncbi.nlm.nih.gov/pubmed/31960547
http://dx.doi.org/10.1111/cas.14312

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