Cargando…

Frequent homozygous deletion of Cdkn2a/2b in tremolite‐induced malignant mesothelioma in rats

The onset of malignant mesothelioma (MM) is linked to exposure to asbestos fibers. Asbestos fibers are classified as serpentine (chrysotile) or amphibole, which includes the crocidolite, amosite, anthophyllite, tremolite, and actinolite types. Although few studies have been undertaken, anthophyllite...

Descripción completa

Detalles Bibliográficos
Autores principales:	Okazaki, Yasumasa, Misawa, Nobuaki, Akatsuka, Shinya, Kohyama, Norihiko, Sekido, Yoshitaka, Takahashi, Takashi, Toyokuni, Shinya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156836/ https://www.ncbi.nlm.nih.gov/pubmed/32080953 http://dx.doi.org/10.1111/cas.14358

Ejemplares similares

RAT MODEL DEMONSTRATES A HIGH RISK OF TREMOLITE BUT A LOW RISK OF ANTHOPHYLLITE FOR MESOTHELIAL CARCINOGENESIS
por: AIERKEN, DILINUER, et al.
Publicado: (2014)

Mysterious link between iron overload and CDKN2A/2B
por: Toyokuni, Shinya
Publicado: (2011)

Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium
por: Ito, Fumiya, et al.
Publicado: (2020)

Overexpression of miR‐199/214 is a distinctive feature of iron‐induced and asbestos‐induced sarcomatoid mesothelioma in rats
por: Okazaki, Yasumasa, et al.
Publicado: (2020)

Carbonic anhydrase 9 confers resistance to ferroptosis/apoptosis in malignant mesothelioma under hypoxia
por: Li, Zan, et al.
Publicado: (2019)

Urokinase-type plasminogen activator receptor promotes proliferation and invasion with reduced cisplatin sensitivity in malignant mesothelioma
por: Wang, Shenqi, et al.
Publicado: (2016)

Phlebotomy as a preventive measure for crocidolite‐induced mesothelioma in male rats
por: Ohara, Yuuki, et al.
Publicado: (2018)

Biological effects of tremolite.
por: Wagner, J. C., et al.
Publicado: (1982)

Connective tissue growth factor-specific monoclonal antibody inhibits growth of malignant mesothelioma in an orthotopic mouse model
por: Ohara, Yuuki, et al.
Publicado: (2018)

CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas
por: Sievers, Philipp, et al.
Publicado: (2020)

CDKN2A/B Homozygous Deletions in Astrocytomas: A Literature Review
por: Yuile, Alexander, et al.
Publicado: (2023)

MPC-10 Prognostic analysis in IDH mutant astrocytoma patient with CDKN2A/B homozygous deletion
por: Yanagisawa, Shunsuke, et al.
Publicado: (2021)

NF2 alteration in mesothelioma
por: Sekido, Yoshitaka, et al.
Publicado: (2023)

The Dust Hazard in Tremolite Talc Mining
por: Greenburg, Leonard
Publicado: (1947)

Impact of CDKN2A/B Homozygous Deletion on the Prognosis and Biology of IDH-Mutant Glioma
por: Huang, L. Eric
Publicado: (2022)

Astaxanthin ameliorates ferric nitrilotriacetate-induced renal oxidative injury in rats
por: Okazaki, Yasumasa, et al.
Publicado: (2017)

BRCA1 haploinsufficiency impairs iron metabolism to promote chrysotile‐induced mesothelioma via ferroptosis resistance
por: Luo, Yaguang, et al.
Publicado: (2023)

NF2/Merlin Inactivation and Potential Therapeutic Targets in Mesothelioma
por: Sato, Tatsuhiro, et al.
Publicado: (2018)

Genome-Scale Approaches to Investigate Oxidative DNA Damage
por: Akatsuka, Shinya, et al.
Publicado: (2010)

Clinical significance of CDKN2A homozygous deletion in combination with methylated MGMT status for IDH‐wildtype glioblastoma
por: Funakoshi, Yusuke, et al.
Publicado: (2021)

Loss of p16 expression is a sensitive marker of CDKN2A homozygous deletion in malignant meningiomas
por: Tang, Vivian, et al.
Publicado: (2023)

P16 immunohistochemistry is a sensitive and specific surrogate marker for CDKN2A homozygous deletion in gliomas
por: Vij, Meenakshi, et al.
Publicado: (2023)

FISH assay development for the detection of p16/CDKN2A deletion in malignant pleural mesothelioma
por: Chung, Catherine T-S, et al.
Publicado: (2010)

Fenton Reaction Induced Cancer in Wild Type Rats Recapitulates Genomic Alterations Observed in Human Cancer
por: Akatsuka, Shinya, et al.
Publicado: (2012)

Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice
por: Badhai, Jitendra, et al.
Publicado: (2020)

Carcinogenesis as Side Effects of Iron and Oxygen Utilization: From the Unveiled Truth toward Ultimate Bioengineering
por: Toyokuni, Shinya, et al.
Publicado: (2020)

Homozygous Co-Deletion of Type I Interferons and CDKN2A Genes in Thoracic Cancers: Potential Consequences for Therapy
por: Grard, Marion, et al.
Publicado: (2021)

SDPS-27 P16 IMMUNOHISTOCHEMISTRY AS A SCREENING TOOL FOR HOMOZYGOUS CDKN2A DELETIONS IN GLIAL TUMORS
por: Zschernack, Valentina, et al.
Publicado: (2023)

Metamorphosis of mesothelial cells with active horizontal motility in tissue culture
por: Nagai, Hirotaka, et al.
Publicado: (2013)

Met Is the Most Frequently Amplified Gene in Endometriosis-Associated Ovarian Clear Cell Adenocarcinoma and Correlates with Worsened Prognosis
por: Yamashita, Yoriko, et al.
Publicado: (2013)

Evaluation of two distinct methods to quantify the uptake of crocidolite fibers by mesothelial cells
por: Yamashita, Kyoko, et al.
Publicado: (2013)

Occurrence and characterization of tremolite asbestos from the Mid Atlantic Ridge
por: Di Giuseppe, Dario, et al.
Publicado: (2021)

An unusual recurrent high-grade glioneuronal tumor with MAP2K1 mutation and CDKN2A/B homozygous deletion
por: Cheaney, Barry, et al.
Publicado: (2019)

Homozygous deletion of CDKN2A by fluorescence in situ hybridization is prognostic in grade 4, but not grade 2 or 3, IDH-mutant astrocytomas
por: Marker, Daniel F., et al.
Publicado: (2020)

Frequent deletion of the CDKN2A locus in chordoma: analysis of chromosomal imbalances using array comparative genomic hybridisation
por: Hallor, K H, et al.
Publicado: (2008)

Surface reactivity of amphibole asbestos: a comparison between crocidolite and tremolite
por: Andreozzi, Giovanni B., et al.
Publicado: (2017)

Co‐occurrence of CDKN2A/B and IFN‐I homozygous deletions correlates with an immunosuppressive phenotype and poor prognosis in lung adenocarcinoma
por: Peng, Yuan, et al.
Publicado: (2022)

CDKN2A Determines Mesothelioma Cell Fate to EZH2 Inhibition
por: Pinton, Giulia, et al.
Publicado: (2021)

RhoA and vigilin are candidates for immunohistochemical markers for epithelioid malignant mesothelioma
por: Hiratsuka, Takuya, et al.
Publicado: (2022)

Targeting the Hippo Pathway Is a New Potential Therapeutic Modality for Malignant Mesothelioma
por: Sekido, Yoshitaka
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ft8kmuc6mr5flutt5dg8u934b1