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Phase 1b/2 study of blinatumomab in Japanese adults with relapsed/refractory acute lymphoblastic leukemia
Adult patients with relapsed/refractory (R/R) B‐precursor acute lymphoblastic leukemia (ALL) have a poor prognosis. Blinatumomab is a bispecific T‐cell engager (BiTE) immuno‐oncology therapy with dual specificity for CD19 and CD3 that redirects patients’ CD3‐positive cytotoxic T cells to lyse malign...
Autores principales: | Kiyoi, Hitoshi, Morris, Joan D., Oh, Iekuni, Maeda, Yoshinobu, Minami, Hironobu, Miyamoto, Toshihiro, Sakura, Toru, Iida, Hiroatsu, Tuglus, Catherine A., Chen, Yuqi, Dos Santos, Cedric, Kalabus, James, Anderson, Abraham, Hata, Tomoko, Nakashima, Yasuhiro, Kobayashi, Yukio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156857/ https://www.ncbi.nlm.nih.gov/pubmed/31971321 http://dx.doi.org/10.1111/cas.14322 |
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