Ligand-induced conformational changes in a SMALP-encapsulated GPCR.

The adenosine 2A receptor (A(2A)R), a G-protein-coupled receptor (GPCR), was solubilised and purified encapsulated in styrene maleic acid lipid particles (SMALPs). The purified A(2A)R-SMALP was associated with phospholipids characteristic of the plasma membrane of Pichia pastoris, the host used for...

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Detalles Bibliográficos
Autores principales: Routledge, Sarah J., Jamshad, Mohammed, Little, Haydn A., Lin, Yu-Pin, Simms, John, Thakker, Alpesh, Spickett, Corinne M., Bill, Roslyn M., Dafforn, Tim R., Poyner, David R., Wheatley, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156913/
https://www.ncbi.nlm.nih.gov/pubmed/32126232
http://dx.doi.org/10.1016/j.bbamem.2020.183235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156913/
https://www.ncbi.nlm.nih.gov/pubmed/32126232
http://dx.doi.org/10.1016/j.bbamem.2020.183235

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