Evaluation of the abuse potential of pitolisant, a selective H(3)-receptor antagonist/inverse agonist, for the treatment of adult patients with narcolepsy with or without cataplexy

OBJECTIVES: To evaluate the human abuse potential of pitolisant, a selective histamine 3 (H(3))-receptor antagonist/inverse agonist recently approved by the US Food and Drug Administration for the treatment of excessive daytime sleepiness in adult patients with narcolepsy. METHODS: Nondependent, rec...

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Detalles Bibliográficos
Autores principales: Setnik, Beatrice, McDonnell, Michael, Mills, Catherine, Scart-Grès, Catherine, Robert, Philippe, Dayno, Jeffrey M, Schwartz, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Neurological Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157189/
https://www.ncbi.nlm.nih.gov/pubmed/31626696
http://dx.doi.org/10.1093/sleep/zsz252

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