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Broad Protection of Pigs against Heterologous PRRSV Strains by a GP5-Mosaic DNA Vaccine Prime/GP5-Mosaic rVaccinia (VACV) Vaccine Boost

Background: Porcine reproductive and respiratory syndrome (PRRS) viruses are a major cause of disease and economic loss in pigs worldwide. High genetic diversity among PRRSV strains is problematic for successful disease control by vaccination. Mosaic DNA and vaccinia (VACV) vaccines were developed i...

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Detalles Bibliográficos
Autores principales: Cui, Junru, O’Connell, Caitlin M., Hagen, Connor, Sawicki, Kim, Smyth, Joan A., Verardi, Paulo H., Van Kruiningen, Herbert J., Garmendia, Antonio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157218/
https://www.ncbi.nlm.nih.gov/pubmed/32121277
http://dx.doi.org/10.3390/vaccines8010106