A Lassa Virus Live-Attenuated Vaccine Candidate Based on Rearrangement of the Intergenic Region

Lassa virus (LASV) poses a significant public health problem within the regions of Lassa fever endemicity in Western Africa. LASV infects several hundred thousand individuals yearly, and a considerable number of Lassa fever cases are associated with high morbidity and lethality. No approved LASV vac...

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Detalles Bibliográficos
Autores principales: Cai, Yingyun, Iwasaki, Masaharu, Motooka, Daisuke, Liu, David X., Yu, Shuiqing, Cooper, Kurt, Hart, Randy, Adams, Ricky, Burdette, Tracey, Postnikova, Elena N., Kurtz, Jonathan, St. Claire, Marisa, Ye, Chengjin, Kuhn, Jens H., Martínez-Sobrido, Luis, de la Torre, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157513/
https://www.ncbi.nlm.nih.gov/pubmed/32209677
http://dx.doi.org/10.1128/mBio.00186-20

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