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Product Development Partnerships: Delivering Innovation for the Elimination of African Trypanosomiasis?

African trypanosomiasis has been labelled as a ‘tool-deficient’ disease. This article reflects on the role that Product Development Partnerships (PDPs) have played in delivering new tools and innovations for the control and elimination of the African trypanosomiases. We analysed three product develo...

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Detalles Bibliográficos
Autores principales: Taylor, Emma Michelle, Smith, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157598/
https://www.ncbi.nlm.nih.gov/pubmed/31952121
http://dx.doi.org/10.3390/tropicalmed5010011
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author Taylor, Emma Michelle
Smith, James
author_facet Taylor, Emma Michelle
Smith, James
author_sort Taylor, Emma Michelle
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description African trypanosomiasis has been labelled as a ‘tool-deficient’ disease. This article reflects on the role that Product Development Partnerships (PDPs) have played in delivering new tools and innovations for the control and elimination of the African trypanosomiases. We analysed three product development partnerships—DNDi, FIND and GALVmed—that focus on delivering new drugs, diagnostic tests, and animal health innovations, respectively. We interviewed key informants within each of the organisations to understand how they delivered new innovations. While it is too early (and beyond the scope of this article) to assess the role of these three organisations in accelerating the elimination of the African trypanosomiases, all three organisations have been responsible for delivering new innovations for diagnosis and treatment through brokering and incentivising innovation and private sector involvement. It is doubtful that these innovations would have been delivered without them. To varying degrees, all three organisations are evolving towards a greater brokering role, away from only product development, prompted by donors. On balance, PDPs have an important role to play in delivering health innovations, and donors need to reflect on how best to incentivise them to focus and continue to deliver new products.
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spelling pubmed-71575982020-05-01 Product Development Partnerships: Delivering Innovation for the Elimination of African Trypanosomiasis? Taylor, Emma Michelle Smith, James Trop Med Infect Dis Article African trypanosomiasis has been labelled as a ‘tool-deficient’ disease. This article reflects on the role that Product Development Partnerships (PDPs) have played in delivering new tools and innovations for the control and elimination of the African trypanosomiases. We analysed three product development partnerships—DNDi, FIND and GALVmed—that focus on delivering new drugs, diagnostic tests, and animal health innovations, respectively. We interviewed key informants within each of the organisations to understand how they delivered new innovations. While it is too early (and beyond the scope of this article) to assess the role of these three organisations in accelerating the elimination of the African trypanosomiases, all three organisations have been responsible for delivering new innovations for diagnosis and treatment through brokering and incentivising innovation and private sector involvement. It is doubtful that these innovations would have been delivered without them. To varying degrees, all three organisations are evolving towards a greater brokering role, away from only product development, prompted by donors. On balance, PDPs have an important role to play in delivering health innovations, and donors need to reflect on how best to incentivise them to focus and continue to deliver new products. MDPI 2020-01-15 /pmc/articles/PMC7157598/ /pubmed/31952121 http://dx.doi.org/10.3390/tropicalmed5010011 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Taylor, Emma Michelle
Smith, James
Product Development Partnerships: Delivering Innovation for the Elimination of African Trypanosomiasis?
title Product Development Partnerships: Delivering Innovation for the Elimination of African Trypanosomiasis?
title_full Product Development Partnerships: Delivering Innovation for the Elimination of African Trypanosomiasis?
title_fullStr Product Development Partnerships: Delivering Innovation for the Elimination of African Trypanosomiasis?
title_full_unstemmed Product Development Partnerships: Delivering Innovation for the Elimination of African Trypanosomiasis?
title_short Product Development Partnerships: Delivering Innovation for the Elimination of African Trypanosomiasis?
title_sort product development partnerships: delivering innovation for the elimination of african trypanosomiasis?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157598/
https://www.ncbi.nlm.nih.gov/pubmed/31952121
http://dx.doi.org/10.3390/tropicalmed5010011
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