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Evaluation of the Potency of Two Pyolysin-Derived Recombinant Proteins as Vaccine Candidates of Trueperella Pyogenes in a Mouse Model: Pyolysin Oligomerization and Structural Change Affect the Efficacy of Pyolysin-Based Vaccines

Trueperella pyogenes (T. pyogenes) is an important opportunistic pathogen in livestock and wild animals. However, only one commercial T. pyogenes vaccine is currently available, and its immunoprotective effect is not ideal. Pyolysin (PLO) is one of the important virulence factors expressed by T. pyo...

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Detalles Bibliográficos
Autores principales:	Yang, Lingxiao, Liang, Hongmin, Wang, Bing, Ma, Bo, Wang, Junwei, Zhang, Wenlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157609/ https://www.ncbi.nlm.nih.gov/pubmed/32050696 http://dx.doi.org/10.3390/vaccines8010079

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