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Development of an IL-17A DNA Vaccine to Treat Systemic Lupus Erythematosus in Mice

The interleukin-17 (IL-17) family, especially IL-17A, plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). This study developed an IL-17A epitope vaccine to treat SLE in NZBWF1 and MRL/lpr mouse models. A plasmid vector encoding a hepatitis B core (HBc)-IL-17A epitope f...

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Detalles Bibliográficos
Autores principales:	Koriyama, Hiroshi, Ikeda, Yuka, Nakagami, Hironori, Shimamura, Munehisa, Yoshida, Shota, Rakugi, Hiromi, Morishita, Ryuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157613/ https://www.ncbi.nlm.nih.gov/pubmed/32059488 http://dx.doi.org/10.3390/vaccines8010083

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