In Vitro Production and Immunogenicity of a Clostridium difficile Spore-Specific BclA3 Glycopeptide Conjugate Vaccine

The BclA3 glycoprotein is a major component of the exosporangial layer of Clostridium difficile spores and in this study we demonstrate that this glycoprotein is a major spore surface associated antigen. Here, we confirm the role of SgtA glycosyltransferase (SgtA GT) in BclA3 glycosylation and recap...

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Detalles Bibliográficos
Autores principales: Aubry, Annie, Zou, Wei, Vinogradov, Evguenii, Williams, Dean, Chen, Wangxue, Harris, Greg, Zhou, Hongyan, Schur, Melissa J., Gilbert, Michel, Douce, Gillian R., Logan, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157674/
https://www.ncbi.nlm.nih.gov/pubmed/32046000
http://dx.doi.org/10.3390/vaccines8010073

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