Cargando…
Effective Activation of Human Antigen-Presenting Cells and Cytotoxic CD8(+) T Cells by a Calcium Phosphate-Based Nanoparticle Vaccine Delivery System
The ability of vaccines to induce T cell responses is crucial for preventing diseases caused by viruses. Nanoparticles (NPs) are considered to be efficient tools for the initiation of potent immune responses. Calcium phosphate (CaP) NPs are a class of biodegradable nanocarriers that are able to deli...
Autores principales: | Scheffel, Florian, Knuschke, Torben, Otto, Lucas, Kollenda, Sebastian, Sokolova, Viktoriya, Cosmovici, Christine, Buer, Jan, Timm, Jörg, Epple, Matthias, Westendorf, Astrid M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157756/ https://www.ncbi.nlm.nih.gov/pubmed/32121590 http://dx.doi.org/10.3390/vaccines8010110 |
Ejemplares similares
-
Local delivery of siRNA-loaded calcium phosphate nanoparticles abates pulmonary inflammation
por: Frede, Annika, et al.
Publicado: (2017) -
A Combination of Anti-PD-L1 Treatment and Therapeutic Vaccination Facilitates Improved Retroviral Clearance via Reactivation of Highly Exhausted T Cells
por: Knuschke, Torben, et al.
Publicado: (2021) -
Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8(+) T Cell Responses During Chronic Retroviral Infection
por: Knuschke, Torben, et al.
Publicado: (2018) -
Combination of nanoparticle-based therapeutic vaccination and transient ablation of regulatory T cells enhances anti-viral immunity during chronic retroviral infection
por: Knuschke, Torben, et al.
Publicado: (2016) -
Biological and Medical Applications of Calcium Phosphate Nanoparticles
por: Sokolova, Viktoriya, et al.
Publicado: (2021)