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Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature

Peripartum pancreatitis is a rare clinical condition that occurs usually in the third trimester of pregnancy. Pancreatitis is usually secondary to gallstones, and it can lead to life-threatening and rare complications. We report a case of necrotizing postpartum pancreatitis that developed abdominal...

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Autores principales: Ali, Syed Muhammad, Shaikh, Nissar Ahmed, Aftab, Zia, Latif, Ejaz, Sameer, Muhammad, Khan, Muhammad Burhan, Al-Tarakji, Mohannad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157796/
https://www.ncbi.nlm.nih.gov/pubmed/32309004
http://dx.doi.org/10.1155/2020/5785413
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author Ali, Syed Muhammad
Shaikh, Nissar Ahmed
Aftab, Zia
Latif, Ejaz
Sameer, Muhammad
Khan, Muhammad Burhan
Al-Tarakji, Mohannad
author_facet Ali, Syed Muhammad
Shaikh, Nissar Ahmed
Aftab, Zia
Latif, Ejaz
Sameer, Muhammad
Khan, Muhammad Burhan
Al-Tarakji, Mohannad
author_sort Ali, Syed Muhammad
collection PubMed
description Peripartum pancreatitis is a rare clinical condition that occurs usually in the third trimester of pregnancy. Pancreatitis is usually secondary to gallstones, and it can lead to life-threatening and rare complications. We report a case of necrotizing postpartum pancreatitis that developed abdominal compartment syndrome (ACS) in early course, posterior reversible encephalopathy syndrome (PRES), and splanchnic and extrasplanchnic thrombosis later on. Case. 31-year-old female, one week after delivery, presented to the emergency department with abdominal pain, nausea and vomiting, tenderness in the epigastrium, and raised pancreatic enzymes. Ultrasound (USG) showed bulky pancreas with gallstones. She was diagnosed as having acute biliary pancreatitis and started to be hydrated and was supplemented with analgesia. Her condition deteriorated on the 2(nd) day, and she was shifted to the surgical intensive care unit (SICU) where she developed abdominal compartment syndrome (ACS), respiratory distress, and acute kidney injury, requiring endotracheal intubation and ventilation. Computerized tomography (CT) showed pancreatic necrosis with multiple fluid collections and significant left-sided pleural effusion. Percutaneous drainage of pleural effusion was done, and she was stabilized to be weaned off from mechanical ventilation. On day 15, she underwent USG-guided drainage of the pancreatic collection and ERCP (endoscopic retrograde cholangiopancreatography) on day 19. Post-ERCP, she had tonic colonic convulsions which were treated with benzodiazepines and phenytoin. It was diagnosed by imaging studies as posterior reversible encephalopathy syndrome (PRES). Her abdomen was still distended and tender; CT showed a significant pseudocyst with splanchnic and extrasplanchnic thrombosis. She had laparotomy, gastrocystostomy, and cholecystectomy on day 28th. She made uncomplicated recovery and discharged in good health. Conclusion. Peripartum pancreatitis can be complicated by ACS, PRES, and splanchnic and extrasplanchnic thrombosis.
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spelling pubmed-71577962020-04-17 Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature Ali, Syed Muhammad Shaikh, Nissar Ahmed Aftab, Zia Latif, Ejaz Sameer, Muhammad Khan, Muhammad Burhan Al-Tarakji, Mohannad Case Rep Surg Case Report Peripartum pancreatitis is a rare clinical condition that occurs usually in the third trimester of pregnancy. Pancreatitis is usually secondary to gallstones, and it can lead to life-threatening and rare complications. We report a case of necrotizing postpartum pancreatitis that developed abdominal compartment syndrome (ACS) in early course, posterior reversible encephalopathy syndrome (PRES), and splanchnic and extrasplanchnic thrombosis later on. Case. 31-year-old female, one week after delivery, presented to the emergency department with abdominal pain, nausea and vomiting, tenderness in the epigastrium, and raised pancreatic enzymes. Ultrasound (USG) showed bulky pancreas with gallstones. She was diagnosed as having acute biliary pancreatitis and started to be hydrated and was supplemented with analgesia. Her condition deteriorated on the 2(nd) day, and she was shifted to the surgical intensive care unit (SICU) where she developed abdominal compartment syndrome (ACS), respiratory distress, and acute kidney injury, requiring endotracheal intubation and ventilation. Computerized tomography (CT) showed pancreatic necrosis with multiple fluid collections and significant left-sided pleural effusion. Percutaneous drainage of pleural effusion was done, and she was stabilized to be weaned off from mechanical ventilation. On day 15, she underwent USG-guided drainage of the pancreatic collection and ERCP (endoscopic retrograde cholangiopancreatography) on day 19. Post-ERCP, she had tonic colonic convulsions which were treated with benzodiazepines and phenytoin. It was diagnosed by imaging studies as posterior reversible encephalopathy syndrome (PRES). Her abdomen was still distended and tender; CT showed a significant pseudocyst with splanchnic and extrasplanchnic thrombosis. She had laparotomy, gastrocystostomy, and cholecystectomy on day 28th. She made uncomplicated recovery and discharged in good health. Conclusion. Peripartum pancreatitis can be complicated by ACS, PRES, and splanchnic and extrasplanchnic thrombosis. Hindawi 2020-04-02 /pmc/articles/PMC7157796/ /pubmed/32309004 http://dx.doi.org/10.1155/2020/5785413 Text en Copyright © 2020 Syed Muhammad Ali et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ali, Syed Muhammad
Shaikh, Nissar Ahmed
Aftab, Zia
Latif, Ejaz
Sameer, Muhammad
Khan, Muhammad Burhan
Al-Tarakji, Mohannad
Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature
title Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature
title_full Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature
title_fullStr Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature
title_full_unstemmed Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature
title_short Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature
title_sort peripartum severe acute pancreatitis with rare complications: case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157796/
https://www.ncbi.nlm.nih.gov/pubmed/32309004
http://dx.doi.org/10.1155/2020/5785413
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