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Low-Dose Decitabine Assists Human Umbilical Cord-Derived Mesenchymal Stem Cells in Protecting β Cells via the Modulation of the Macrophage Phenotype in Type 2 Diabetic Mice

BACKGROUND: Progressive β-cell dysfunction, a major characteristic of type 2 diabetes (T2D), is closely related to the infiltration of inflammatory macrophages within islets. Mesenchymal stem cells (MSCs) have been identified to alleviate β-cell dysfunction by modulating macrophage phenotype in T2D,...

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Detalles Bibliográficos
Autores principales: Xue, Jing, Cheng, Yu, Hao, Haojie, Gao, Jieqing, Yin, Yaqi, Yu, Songyan, Zou, Junyan, Liu, Jiejie, Zhang, Qi, Mu, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157805/
https://www.ncbi.nlm.nih.gov/pubmed/32322278
http://dx.doi.org/10.1155/2020/4689798