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Vitamin C Treatment Rescues Prelamin A-Induced Premature Senescence of Subchondral Bone Mesenchymal Stem Cells

Aging is a predominant risk factor for many chronic conditions. Stem cell dysfunction plays a pivotal role in the aging process. Prelamin A, an abnormal processed form of the nuclear lamina protein lamin A, has been reported to trigger premature senescence. However, the mechanism driving stem cell d...

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Detalles Bibliográficos
Autores principales: Qu, Yan-Nv, Zhang, Li, Wang, Ting, Zhang, He-Yang, Yang, Ze-Ji, Yuan, Fang-Fang, Wang, Yan, Li, Si-Wei, Jiang, Xiao-Xia, Xie, Xiao-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157810/
https://www.ncbi.nlm.nih.gov/pubmed/32322277
http://dx.doi.org/10.1155/2020/3150716