Hiding in Plain Sight: an Approach to Treating Patients with Severe COVID-19 Infection

Patients with COVID-19 infection are at risk of acute respiratory disease syndrome (ARDS) and death. The tissue receptor for COVID-19 is ACE2, and higher levels of ACE2 can protect against ARDS. Angiotensin receptor blockers and statins upregulate ACE2. Clinical trials are needed to determine whethe...

Descripción completa

Detalles Bibliográficos
Autores principales: Fedson, David S., Opal, Steven M., Rordam, Ole Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157814/
https://www.ncbi.nlm.nih.gov/pubmed/32198163
http://dx.doi.org/10.1128/mBio.00398-20
Descripción
Sumario:Patients with COVID-19 infection are at risk of acute respiratory disease syndrome (ARDS) and death. The tissue receptor for COVID-19 is ACE2, and higher levels of ACE2 can protect against ARDS. Angiotensin receptor blockers and statins upregulate ACE2. Clinical trials are needed to determine whether this drug combination might be used to treat patients with severe COVID-19 infection.

Ejemplares similares