A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating

While the basic mechanisms of flavivirus entry and fusion are understood, little is known about the postfusion events that precede RNA replication, such as nucleocapsid disassembly. We describe here a sensitive, conditionally replication-defective yellow fever virus (YFV) entry reporter, YFVΔSK/Nluc...

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Detalles Bibliográficos
Autores principales: Ramanathan, Harish N., Zhang, Shuo, Douam, Florian, Mar, Katrina B., Chang, Jinhong, Yang, Priscilla L., Schoggins, John W., Ploss, Alexander, Lindenbach, Brett D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157815/
https://www.ncbi.nlm.nih.gov/pubmed/32291299
http://dx.doi.org/10.1128/mBio.00467-20

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