Global Trends in Proteome Remodeling of the Outer Membrane Modulate Antimicrobial Permeability in Klebsiella pneumoniae

In Gram-negative bacteria, the permeability of the outer membrane governs rates of antibiotic uptake and thus the efficacy of antimicrobial treatment. Hydrophilic drugs like β-lactam antibiotics depend on diffusion through pore-forming outer membrane proteins to reach their intracellular targets. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Rocker, Andrea, Lacey, Jake A., Belousoff, Matthew J., Wilksch, Jonathan J., Strugnell, Richard A., Davies, Mark R., Lithgow, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157821/
https://www.ncbi.nlm.nih.gov/pubmed/32291303
http://dx.doi.org/10.1128/mBio.00603-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157821/
https://www.ncbi.nlm.nih.gov/pubmed/32291303
http://dx.doi.org/10.1128/mBio.00603-20

Ejemplares similares