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Global Trends in Proteome Remodeling of the Outer Membrane Modulate Antimicrobial Permeability in Klebsiella pneumoniae

In Gram-negative bacteria, the permeability of the outer membrane governs rates of antibiotic uptake and thus the efficacy of antimicrobial treatment. Hydrophilic drugs like β-lactam antibiotics depend on diffusion through pore-forming outer membrane proteins to reach their intracellular targets. In...

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Detalles Bibliográficos
Autores principales:	Rocker, Andrea, Lacey, Jake A., Belousoff, Matthew J., Wilksch, Jonathan J., Strugnell, Richard A., Davies, Mark R., Lithgow, Trevor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157821/ https://www.ncbi.nlm.nih.gov/pubmed/32291303 http://dx.doi.org/10.1128/mBio.00603-20

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