Inhibition of ribonucleotide reductase and growth of human colon carcinoma HT-29 cells and mouse leukemia L1210 cells by N-hydroxy-N′-aminoguanidine derivatives

A series of N-hydroxy-N′-aminoguanidine (HAG) derivatives were studied and compared for their effects on ribonucleotide reductase activity in cell-free extracts; on nucleic acid synthesis and the growth of human colon carcinoma HT-29 cells; and on mouse leukemia L1210 cells in culture. The HAG deriv...

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Detalles Bibliográficos
Autores principales: Masahiko, Matsumoto, Fox, John G., Pou-Hsiung, Wang, Koneru, Phanesh B., Lien, Eric J., Cory, Joseph G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 1990
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157920/
https://www.ncbi.nlm.nih.gov/pubmed/2242014
http://dx.doi.org/10.1016/0006-2952(90)90356-P

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