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Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cells

Porcine reproductive and respiratory syndrome (PRRS) is an emerged disease of swine characterized by negligible response of type I IFNs and viral persistence. We show that the PRRSV non-structural protein 1 (Nsp1) is the viral component responsible for modulation of IFN response. Nsp1 blocked dsRNA-...

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Detalles Bibliográficos
Autores principales:	Kim, Oekyung, Sun, Yan, Lai, Frances W., Song, Cheng, Yoo, Dongwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157927/ https://www.ncbi.nlm.nih.gov/pubmed/20416917 http://dx.doi.org/10.1016/j.virol.2010.03.039

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