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The 2–5 A system: Modulation of viral and cellular processes through acceleration of RNA degradation
The 2–5A system is an RNA degradation pathway that can be induced by the interferons (IFNs). Treatment of cells with IFN activates genes encoding several double-stranded RNA (dsRNA)-dependent synthetases. These enzymes generate 5′-triphosphorylated, 2′,5′-phosphodiester-linked oligoadenylates (2–5A)...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Published by Elsevier Inc.
1998
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157933/ https://www.ncbi.nlm.nih.gov/pubmed/9623881 http://dx.doi.org/10.1016/S0163-7258(97)00167-8 |