Garlic extract in prosthesis-related infections: a literature review

With the increasing use of joint replacement surgery, the prevalence of periprosthetic joint infections (PJI) has also increased. However, treating PJI has become a challenge for orthopaedic surgeons because of the prevalence of multi-drug resistant (MDR) bacteria and the formation of protective bio...

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Detalles Bibliográficos
Autores principales: Zhu, Xing-Yang, Zeng, Yi-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157972/
https://www.ncbi.nlm.nih.gov/pubmed/32290752
http://dx.doi.org/10.1177/0300060520913778
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author Zhu, Xing-Yang
Zeng, Yi-Rong
author_facet Zhu, Xing-Yang
Zeng, Yi-Rong
author_sort Zhu, Xing-Yang
collection PubMed
description With the increasing use of joint replacement surgery, the prevalence of periprosthetic joint infections (PJI) has also increased. However, treating PJI has become a challenge for orthopaedic surgeons because of the prevalence of multi-drug resistant (MDR) bacteria and the formation of protective biofilms. Numerous studies have shown that garlic extract (GE) has antibacterial activities and might be a good candidate for PJI treatment. This review explores the antibacterial and antibiofilm activities of GE and its potential to be used in the treatment of PJI.
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spelling pubmed-71579722020-04-20 Garlic extract in prosthesis-related infections: a literature review Zhu, Xing-Yang Zeng, Yi-Rong J Int Med Res Review With the increasing use of joint replacement surgery, the prevalence of periprosthetic joint infections (PJI) has also increased. However, treating PJI has become a challenge for orthopaedic surgeons because of the prevalence of multi-drug resistant (MDR) bacteria and the formation of protective biofilms. Numerous studies have shown that garlic extract (GE) has antibacterial activities and might be a good candidate for PJI treatment. This review explores the antibacterial and antibiofilm activities of GE and its potential to be used in the treatment of PJI. SAGE Publications 2020-04-14 /pmc/articles/PMC7157972/ /pubmed/32290752 http://dx.doi.org/10.1177/0300060520913778 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Zhu, Xing-Yang
Zeng, Yi-Rong
Garlic extract in prosthesis-related infections: a literature review
title Garlic extract in prosthesis-related infections: a literature review
title_full Garlic extract in prosthesis-related infections: a literature review
title_fullStr Garlic extract in prosthesis-related infections: a literature review
title_full_unstemmed Garlic extract in prosthesis-related infections: a literature review
title_short Garlic extract in prosthesis-related infections: a literature review
title_sort garlic extract in prosthesis-related infections: a literature review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157972/
https://www.ncbi.nlm.nih.gov/pubmed/32290752
http://dx.doi.org/10.1177/0300060520913778
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