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A drug identification model developed using deep learning technologies: experience of a medical center in Taiwan

BACKGROUND: Issuing of correct prescriptions is a foundation of patient safety. Medication errors represent one of the most important problems in health care, with ‘look-alike and sound-alike’ (LASA) being the lead error. Existing solutions to prevent LASA still have their limitations. Deep learning...

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Autores principales: Ting, Hsien-Wei, Chung, Sheng-Luen, Chen, Chih-Fang, Chiu, Hsin-Yi, Hsieh, Yow-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158008/
https://www.ncbi.nlm.nih.gov/pubmed/32293426
http://dx.doi.org/10.1186/s12913-020-05166-w
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author Ting, Hsien-Wei
Chung, Sheng-Luen
Chen, Chih-Fang
Chiu, Hsin-Yi
Hsieh, Yow-Wen
author_facet Ting, Hsien-Wei
Chung, Sheng-Luen
Chen, Chih-Fang
Chiu, Hsin-Yi
Hsieh, Yow-Wen
author_sort Ting, Hsien-Wei
collection PubMed
description BACKGROUND: Issuing of correct prescriptions is a foundation of patient safety. Medication errors represent one of the most important problems in health care, with ‘look-alike and sound-alike’ (LASA) being the lead error. Existing solutions to prevent LASA still have their limitations. Deep learning techniques have revolutionized identification classifiers in many fields. In search of better image-based solutions for blister package identification problem, this study using a baseline deep learning drug identification (DLDI) aims to understand how identification confusion of look-alike images by human occurs through the cognitive counterpart of deep learning solutions and thereof to suggest further solutions to approach them. METHODS: We collected images of 250 types of blister-packaged drug from the Out-Patient Department (OPD) of a medical center for identification. The deep learning framework of You Only Look Once (YOLO) was adopted for implementation of the proposed deep learning. The commonly-used F1 score, defined by precision and recall for large numbers of identification tests, was used as the performance criterion. This study trained and compared the proposed models based on images of either the front-side or back-side of blister-packaged drugs. RESULTS: Our results showed that the total training time for the front-side model and back-side model was 5 h 34 min and 7 h 42 min, respectively. The F1 score of the back-side model (95.99%) was better than that of the front-side model (93.72%). CONCLUSIONS: In conclusion, this study constructed a deep learning-based model for blister-packaged drug identification, with an accuracy greater than 90%. This model outperformed identification using conventional computer vision solutions, and could assist pharmacists in identifying drugs while preventing medication errors caused by look-alike blister packages. By integration into existing prescription systems in hospitals, the results of this study indicated that using this model, drugs dispensed could be verified in order to achieve automated prescription and dispensing.
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spelling pubmed-71580082020-04-20 A drug identification model developed using deep learning technologies: experience of a medical center in Taiwan Ting, Hsien-Wei Chung, Sheng-Luen Chen, Chih-Fang Chiu, Hsin-Yi Hsieh, Yow-Wen BMC Health Serv Res Research Article BACKGROUND: Issuing of correct prescriptions is a foundation of patient safety. Medication errors represent one of the most important problems in health care, with ‘look-alike and sound-alike’ (LASA) being the lead error. Existing solutions to prevent LASA still have their limitations. Deep learning techniques have revolutionized identification classifiers in many fields. In search of better image-based solutions for blister package identification problem, this study using a baseline deep learning drug identification (DLDI) aims to understand how identification confusion of look-alike images by human occurs through the cognitive counterpart of deep learning solutions and thereof to suggest further solutions to approach them. METHODS: We collected images of 250 types of blister-packaged drug from the Out-Patient Department (OPD) of a medical center for identification. The deep learning framework of You Only Look Once (YOLO) was adopted for implementation of the proposed deep learning. The commonly-used F1 score, defined by precision and recall for large numbers of identification tests, was used as the performance criterion. This study trained and compared the proposed models based on images of either the front-side or back-side of blister-packaged drugs. RESULTS: Our results showed that the total training time for the front-side model and back-side model was 5 h 34 min and 7 h 42 min, respectively. The F1 score of the back-side model (95.99%) was better than that of the front-side model (93.72%). CONCLUSIONS: In conclusion, this study constructed a deep learning-based model for blister-packaged drug identification, with an accuracy greater than 90%. This model outperformed identification using conventional computer vision solutions, and could assist pharmacists in identifying drugs while preventing medication errors caused by look-alike blister packages. By integration into existing prescription systems in hospitals, the results of this study indicated that using this model, drugs dispensed could be verified in order to achieve automated prescription and dispensing. BioMed Central 2020-04-15 /pmc/articles/PMC7158008/ /pubmed/32293426 http://dx.doi.org/10.1186/s12913-020-05166-w Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Ting, Hsien-Wei
Chung, Sheng-Luen
Chen, Chih-Fang
Chiu, Hsin-Yi
Hsieh, Yow-Wen
A drug identification model developed using deep learning technologies: experience of a medical center in Taiwan
title A drug identification model developed using deep learning technologies: experience of a medical center in Taiwan
title_full A drug identification model developed using deep learning technologies: experience of a medical center in Taiwan
title_fullStr A drug identification model developed using deep learning technologies: experience of a medical center in Taiwan
title_full_unstemmed A drug identification model developed using deep learning technologies: experience of a medical center in Taiwan
title_short A drug identification model developed using deep learning technologies: experience of a medical center in Taiwan
title_sort drug identification model developed using deep learning technologies: experience of a medical center in taiwan
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158008/
https://www.ncbi.nlm.nih.gov/pubmed/32293426
http://dx.doi.org/10.1186/s12913-020-05166-w
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