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TLR2 and caspase-1 signaling are critical for bacterial containment but not clearance during craniotomy-associated biofilm infection
BACKGROUND: A craniotomy is required to access the brain for tumor resection or epilepsy treatment, and despite precautionary measures, infectious complications occur at a frequency of 1–3%. Approximately half of craniotomy infections are caused by Staphylococcus aureus (S. aureus) that forms a biof...
Autores principales: | Aldrich, Amy L., Heim, Cortney E., Shi, Wen, Fallet, Rachel W., Duan, Bin, Kielian, Tammy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158029/ https://www.ncbi.nlm.nih.gov/pubmed/32290861 http://dx.doi.org/10.1186/s12974-020-01793-6 |
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