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Efficacy and safety assessment of different dosage of benznidazol for the treatment of Chagas disease in chronic phase in adults (MULTIBENZ study): study protocol for a multicenter randomized Phase II superiority clinical trial
BACKGROUND: Chagas disease (CD) continues to be a neglected infectious disease with one of the largest burdens globally. Despite the modest cure rates in adult chronic patients and its safety profile, benznidazole (BNZ) is still the drug of choice. Its current recommended dose is based on nonrandomi...
Autores principales: | Molina-Morant, D., Fernández, M. L., Bosch-Nicolau, P., Sulleiro, E., Bangher, M., Salvador, F., Sanchez-Montalva, A., Ribeiro, A. L. P., de Paula, A. M. B., Eloi, S., Correa-Oliveira, R., Villar, J. C., Sosa-Estani, S., Molina, I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158046/ https://www.ncbi.nlm.nih.gov/pubmed/32293523 http://dx.doi.org/10.1186/s13063-020-4226-2 |
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