An optimised dosing regimen versus a standard dosing regimen of vancomycin for the treatment of late onset sepsis due to Gram-positive microorganisms in neonates and infants aged less than 90 days (NeoVanc): study protocol for a randomised controlled trial

BACKGROUND: Vancomycin has been used in clinical practice for over 50 years; however, validated, pharmacokinetic (PK) data relating clinical outcomes to different dosing regimens in neonates are lacking. Coagulase negative staphylococci (CoNS) are the most commonly isolated organisms in neonatal, la...

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Autores principales: Hill, Louise F., Turner, Mark A., Lutsar, Irja, Heath, Paul T., Hardy, Pollyanna, Linsell, Louise, Jacqz-Aigrain, Evelyne, Roilides, Emmanuel, Sharland, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158076/
https://www.ncbi.nlm.nih.gov/pubmed/32293527
http://dx.doi.org/10.1186/s13063-020-4184-8

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