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Clinical outcomes of empirical high-dose meropenem in critically ill patients with sepsis and septic shock: a randomized controlled trial

BACKGROUND: Appropriate antimicrobial dosing is challenging because of changes in pharmacokinetics (PK) parameters and an increase in multidrug-resistant (MDR) organisms in critically ill patients. This study aimed to evaluate the effects of an empirical therapy of high-dose versus standard-dose mer...

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Detalles Bibliográficos
Autores principales:	Lertwattanachai, Tospon, Montakantikul, Preecha, Tangsujaritvijit, Viratch, Sanguanwit, Pitsucha, Sueajai, Jetjamnong, Auparakkitanon, Saranya, Dilokpattanamongkol, Pitchaya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158081/ https://www.ncbi.nlm.nih.gov/pubmed/32318268 http://dx.doi.org/10.1186/s40560-020-00442-7

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