Exosome-mediated transfer of miR-93-5p from cancer-associated fibroblasts confer radioresistance in colorectal cancer cells by downregulating FOXA1 and upregulating TGFB3

BACKGROUND: Cancer-associated fibroblasts (CAFs) have been intensively studied in recent studies with aims of finding more concrete evidence on their mechanism of involvement in tumor progression, which is currently unknown. CAFs can secrete exosomes which are loaded with proteins, lipids and RNAs,...

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Detalles Bibliográficos
Autores principales: Chen, Xijuan, Liu, Junqi, Zhang, Qinglan, Liu, Baoxing, Cheng, Yan, Zhang, Yonglei, Sun, Yanan, Ge, Hong, Liu, Yingqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158087/
https://www.ncbi.nlm.nih.gov/pubmed/32293494
http://dx.doi.org/10.1186/s13046-019-1507-2

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