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Knockdown of long non-coding RNA PVT1 induces apoptosis of fibroblast-like synoviocytes through modulating miR-543-dependent SCUBE2 in rheumatoid arthritis

BACKGROUND: Rheumatoid arthritis (RA), a kind of autoimmune disorder, is featured by many physical symptoms and proliferation of fibroblast-like synoviocytes (FLSs). The relevance of long non-coding RNAs (lncRNAs) in the progression of RA has been probed. Hence, the goal of this report was to invest...

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Detalles Bibliográficos
Autores principales: Wang, Junxia, Kong, Xianghui, Hu, Haijian, Shi, Shunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158104/
https://www.ncbi.nlm.nih.gov/pubmed/32293498
http://dx.doi.org/10.1186/s13018-020-01641-6