Cargando…
Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology?
As the field of artificial intelligence and machine learning (AI/ML) for drug discovery is rapidly advancing, we address the question “What is the impact of recent AI/ML trends in the area of Clinical Pharmacology?” We address difficulties and AI/ML developments for target identification, their use...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158211/ https://www.ncbi.nlm.nih.gov/pubmed/31957003 http://dx.doi.org/10.1002/cpt.1795 |
_version_ | 1783522494198579200 |
---|---|
author | Zhavoronkov, Alex Vanhaelen, Quentin Oprea, Tudor I. |
author_facet | Zhavoronkov, Alex Vanhaelen, Quentin Oprea, Tudor I. |
author_sort | Zhavoronkov, Alex |
collection | PubMed |
description | As the field of artificial intelligence and machine learning (AI/ML) for drug discovery is rapidly advancing, we address the question “What is the impact of recent AI/ML trends in the area of Clinical Pharmacology?” We address difficulties and AI/ML developments for target identification, their use in generative chemistry for small molecule drug discovery, and the potential role of AI/ML in clinical trial outcome evaluation. We briefly discuss current trends in the use of AI/ML in health care and the impact of AI/ML context of the daily practice of clinical pharmacologists. |
format | Online Article Text |
id | pubmed-7158211 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71582112020-04-20 Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology? Zhavoronkov, Alex Vanhaelen, Quentin Oprea, Tudor I. Clin Pharmacol Ther Reviews As the field of artificial intelligence and machine learning (AI/ML) for drug discovery is rapidly advancing, we address the question “What is the impact of recent AI/ML trends in the area of Clinical Pharmacology?” We address difficulties and AI/ML developments for target identification, their use in generative chemistry for small molecule drug discovery, and the potential role of AI/ML in clinical trial outcome evaluation. We briefly discuss current trends in the use of AI/ML in health care and the impact of AI/ML context of the daily practice of clinical pharmacologists. John Wiley and Sons Inc. 2020-03-03 2020-04 /pmc/articles/PMC7158211/ /pubmed/31957003 http://dx.doi.org/10.1002/cpt.1795 Text en © 2020 The Authors. Clinical Pharmacology & Therapeutics published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Reviews Zhavoronkov, Alex Vanhaelen, Quentin Oprea, Tudor I. Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology? |
title | Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology? |
title_full | Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology? |
title_fullStr | Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology? |
title_full_unstemmed | Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology? |
title_short | Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology? |
title_sort | will artificial intelligence for drug discovery impact clinical pharmacology? |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158211/ https://www.ncbi.nlm.nih.gov/pubmed/31957003 http://dx.doi.org/10.1002/cpt.1795 |
work_keys_str_mv | AT zhavoronkovalex willartificialintelligencefordrugdiscoveryimpactclinicalpharmacology AT vanhaelenquentin willartificialintelligencefordrugdiscoveryimpactclinicalpharmacology AT opreatudori willartificialintelligencefordrugdiscoveryimpactclinicalpharmacology |