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Risk of Opioid Use Disorder from Exposure to Opioids in the Perioperative Period: A Systematic Review
Opioid use disorder, a major source of morbidity and mortality globally, is regularly linked to opioids given around the time of surgery. Perioperative period, however, is markedly heterogeneous, with the diverse providers using opioids distinctively, and the various drivers of opioid misuse at-play...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kowsar
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158240/ https://www.ncbi.nlm.nih.gov/pubmed/32337175 http://dx.doi.org/10.5812/aapm.101339 |
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author | Malik, Khalid M Imani, Farnad Beckerly, Rena Chovatiya, Rani |
author_facet | Malik, Khalid M Imani, Farnad Beckerly, Rena Chovatiya, Rani |
author_sort | Malik, Khalid M |
collection | PubMed |
description | Opioid use disorder, a major source of morbidity and mortality globally, is regularly linked to opioids given around the time of surgery. Perioperative period, however, is markedly heterogeneous, with the diverse providers using opioids distinctively, and the various drivers of opioid misuse at-play dissimilarly, throughout the perioperative period. The risk of opioid use disorder may, therefore, be different from opioids given at the various phases of perioperative care, and the ensuing recommendations for their use may also be dissimilar. Systematic search and analysis of the pertinent literature, following the accepted standards, showed an overall increased risk of misuse from the perioperative opioids. However, the analyzed studies had significant methodological limitations, and were constrained mainly to the out-patient phase of the perioperative period. Lacking any data, this risk, therefore, is unknown for intraoperative and postoperative recovery periods. Consequently, no firm recommendations can be extended to anesthesia providers generally managing these perioperative stages. Furthermore, with significant methodological limitations, the current recommendations for opioid use after surgery are also arbitrary. Thus, though proposals for perioperative opioid use are formulated in this article, substantive recommendations would require clear delineation of these risks, while avoiding the limitations noted in this review. |
format | Online Article Text |
id | pubmed-7158240 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Kowsar |
record_format | MEDLINE/PubMed |
spelling | pubmed-71582402020-04-24 Risk of Opioid Use Disorder from Exposure to Opioids in the Perioperative Period: A Systematic Review Malik, Khalid M Imani, Farnad Beckerly, Rena Chovatiya, Rani Anesth Pain Med Systematic Review Opioid use disorder, a major source of morbidity and mortality globally, is regularly linked to opioids given around the time of surgery. Perioperative period, however, is markedly heterogeneous, with the diverse providers using opioids distinctively, and the various drivers of opioid misuse at-play dissimilarly, throughout the perioperative period. The risk of opioid use disorder may, therefore, be different from opioids given at the various phases of perioperative care, and the ensuing recommendations for their use may also be dissimilar. Systematic search and analysis of the pertinent literature, following the accepted standards, showed an overall increased risk of misuse from the perioperative opioids. However, the analyzed studies had significant methodological limitations, and were constrained mainly to the out-patient phase of the perioperative period. Lacking any data, this risk, therefore, is unknown for intraoperative and postoperative recovery periods. Consequently, no firm recommendations can be extended to anesthesia providers generally managing these perioperative stages. Furthermore, with significant methodological limitations, the current recommendations for opioid use after surgery are also arbitrary. Thus, though proposals for perioperative opioid use are formulated in this article, substantive recommendations would require clear delineation of these risks, while avoiding the limitations noted in this review. Kowsar 2020-02-19 /pmc/articles/PMC7158240/ /pubmed/32337175 http://dx.doi.org/10.5812/aapm.101339 Text en Copyright © 2020, Anesthesiology and Pain Medicine http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited. |
spellingShingle | Systematic Review Malik, Khalid M Imani, Farnad Beckerly, Rena Chovatiya, Rani Risk of Opioid Use Disorder from Exposure to Opioids in the Perioperative Period: A Systematic Review |
title | Risk of Opioid Use Disorder from Exposure to Opioids in the Perioperative Period: A Systematic Review |
title_full | Risk of Opioid Use Disorder from Exposure to Opioids in the Perioperative Period: A Systematic Review |
title_fullStr | Risk of Opioid Use Disorder from Exposure to Opioids in the Perioperative Period: A Systematic Review |
title_full_unstemmed | Risk of Opioid Use Disorder from Exposure to Opioids in the Perioperative Period: A Systematic Review |
title_short | Risk of Opioid Use Disorder from Exposure to Opioids in the Perioperative Period: A Systematic Review |
title_sort | risk of opioid use disorder from exposure to opioids in the perioperative period: a systematic review |
topic | Systematic Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158240/ https://www.ncbi.nlm.nih.gov/pubmed/32337175 http://dx.doi.org/10.5812/aapm.101339 |
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