Transcriptional dysregulation in developing trigeminal sensory neurons in the LgDel mouse model of DiGeorge 22q11.2 deletion syndrome

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LgDel mice, which model the heterozygous deletion of genes at human chromosome 22q11.2 associated with DiGeorge/22q11.2 deletion syndrome (22q11DS), have cranial nerve and craniofacial dysfunction as well as disrupted suckling, feeding and swallowing, similar to key 22q11DS phenotypes. Divergent tri...

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Autores principales: Maynard, Thomas M, Horvath, Anelia, P Bernot, James, Karpinski, Beverly A, Tavares, Andre L P, Shah, Ankita, Zheng, Qianqian, Spurr, Liam, Olender, Jacqueline, Moody, Sally A, Fraser, Claire M, LaMantia, Anthony-S, Lee, Norman H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158380/
https://www.ncbi.nlm.nih.gov/pubmed/32047912
http://dx.doi.org/10.1093/hmg/ddaa024

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