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Systems Vaccinology for a Live Attenuated Tularemia Vaccine Reveals Unique Transcriptional Signatures That Predict Humoral and Cellular Immune Responses
Background: Tularemia is a potential biological weapon due to its high infectivity and ease of dissemination. This study aimed to characterize the innate and adaptive responses induced by two different lots of a live attenuated tularemia vaccine and compare them to other well-characterized viral vac...
Autores principales: | Natrajan, Muktha S., Rouphael, Nadine, Lai, Lilin, Kazmin, Dmitri, Jensen, Travis L., Weiss, David S., Ibegbu, Chris, Sztein, Marcelo B., Hooper, William F., Hill, Heather, Anderson, Evan J., Johnson, Robert, Sanz, Patrick, Pulendran, Bali, Goll, Johannes B., Mulligan, Mark J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158697/ https://www.ncbi.nlm.nih.gov/pubmed/31878161 http://dx.doi.org/10.3390/vaccines8010004 |
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