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Impact of T(h)1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques
Generating durable humoral immunity through vaccination depends upon effective interactions of follicular helper T (T(fh)) cells with germinal center (GC) B cells. T(h)1 polarization of T(fh) cells is an important process shaping the success of T(fh)-GC B cell interactions by influencing costimulato...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158739/ https://www.ncbi.nlm.nih.gov/pubmed/31827000 http://dx.doi.org/10.1128/JVI.01737-19 |