Cargando…
Impact of T(h)1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques
Generating durable humoral immunity through vaccination depends upon effective interactions of follicular helper T (T(fh)) cells with germinal center (GC) B cells. T(h)1 polarization of T(fh) cells is an important process shaping the success of T(fh)-GC B cell interactions by influencing costimulato...
Autores principales: | Verma, Anil, Schmidt, Brian A., Elizaldi, Sonny R., Nguyen, Nancy K., Walter, Korey A., Beck, Zoltan, Trinh, Hung V., Dinasarapu, Ashok R., Lakshmanappa, Yashavanth Shaan, Rane, Niharika N., Matyas, Gary R., Rao, Mangala, Shen, Xiaoying, Tomaras, Georgia D., LaBranche, Celia C., Reimann, Keith A., Foehl, David H., Gach, Johannes S., Forthal, Donald N., Kozlowski, Pamela A., Amara, Rama R., Iyer, Smita S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158739/ https://www.ncbi.nlm.nih.gov/pubmed/31827000 http://dx.doi.org/10.1128/JVI.01737-19 |
Ejemplares similares
-
Bridging Vaccine-Induced HIV-1 Neutralizing and Effector Antibody Responses in Rabbit and Rhesus Macaque Animal Models
por: Pollara, Justin, et al.
Publicado: (2019) -
A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques
por: Jones, Andrew T., et al.
Publicado: (2018) -
HIV-1 gp120 and Modified Vaccinia Virus Ankara (MVA) gp140 Boost Immunogens Increase Immunogenicity of a DNA/MVA HIV-1 Vaccine
por: Shen, Xiaoying, et al.
Publicado: (2017) -
Priming with DNA Expressing Trimeric HIV V1V2 Alters the Immune Hierarchy Favoring the Development of V2-Specific Antibodies in Rhesus Macaques
por: Devasundaram, Santhi, et al.
Publicado: (2020) -
Cross-Linking of a CD4-Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques
por: Shen, Xiaoying, et al.
Publicado: (2017)