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Impact of T(h)1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques

Generating durable humoral immunity through vaccination depends upon effective interactions of follicular helper T (T(fh)) cells with germinal center (GC) B cells. T(h)1 polarization of T(fh) cells is an important process shaping the success of T(fh)-GC B cell interactions by influencing costimulato...

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Detalles Bibliográficos
Autores principales: Verma, Anil, Schmidt, Brian A., Elizaldi, Sonny R., Nguyen, Nancy K., Walter, Korey A., Beck, Zoltan, Trinh, Hung V., Dinasarapu, Ashok R., Lakshmanappa, Yashavanth Shaan, Rane, Niharika N., Matyas, Gary R., Rao, Mangala, Shen, Xiaoying, Tomaras, Georgia D., LaBranche, Celia C., Reimann, Keith A., Foehl, David H., Gach, Johannes S., Forthal, Donald N., Kozlowski, Pamela A., Amara, Rama R., Iyer, Smita S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158739/
https://www.ncbi.nlm.nih.gov/pubmed/31827000
http://dx.doi.org/10.1128/JVI.01737-19

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