Oleoylethanolamide, A Bioactive Lipid Amide, as A Promising Treatment Strategy for Coronavirus/COVID-19

The current outbreak of COVID-19 (coronavirus) has been identified by World Health Organization (WHO) as a global pandemic. With the emergence of the COVID-19 virus and considering the lack of effective pharmaceutical treatment for it, there is an urgent need to identify safe and effective drugs or...

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Autores principales: Ghaffari, Samad, Roshanravan, Neda, Tutunchi, Helda, Ostadrahimi, Alireza, Pouraghaei, Mahboub, Kafil, Behnam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IMSS. Published by Elsevier Inc. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158763/
https://www.ncbi.nlm.nih.gov/pubmed/32327293
http://dx.doi.org/10.1016/j.arcmed.2020.04.006
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author Ghaffari, Samad
Roshanravan, Neda
Tutunchi, Helda
Ostadrahimi, Alireza
Pouraghaei, Mahboub
Kafil, Behnam
author_facet Ghaffari, Samad
Roshanravan, Neda
Tutunchi, Helda
Ostadrahimi, Alireza
Pouraghaei, Mahboub
Kafil, Behnam
author_sort Ghaffari, Samad
collection PubMed
description The current outbreak of COVID-19 (coronavirus) has been identified by World Health Organization (WHO) as a global pandemic. With the emergence of the COVID-19 virus and considering the lack of effective pharmaceutical treatment for it, there is an urgent need to identify safe and effective drugs or potential adjuvant therapy in this regard. Bioactive lipids with an array of known health-promoting properties can be suggested as effective agents in alleviating acute respiratory stress induced by virus. The bioactive lipid amide, oleoylethanolamide (OEA), due to several distinctive homeostatic properties, including anti-inflammatory activities, modulation of immune response, and anti-oxidant effects can be considered as a novel potential pharmacological alternative for the management of COVID-19.
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spelling pubmed-71587632020-04-15 Oleoylethanolamide, A Bioactive Lipid Amide, as A Promising Treatment Strategy for Coronavirus/COVID-19 Ghaffari, Samad Roshanravan, Neda Tutunchi, Helda Ostadrahimi, Alireza Pouraghaei, Mahboub Kafil, Behnam Arch Med Res Article The current outbreak of COVID-19 (coronavirus) has been identified by World Health Organization (WHO) as a global pandemic. With the emergence of the COVID-19 virus and considering the lack of effective pharmaceutical treatment for it, there is an urgent need to identify safe and effective drugs or potential adjuvant therapy in this regard. Bioactive lipids with an array of known health-promoting properties can be suggested as effective agents in alleviating acute respiratory stress induced by virus. The bioactive lipid amide, oleoylethanolamide (OEA), due to several distinctive homeostatic properties, including anti-inflammatory activities, modulation of immune response, and anti-oxidant effects can be considered as a novel potential pharmacological alternative for the management of COVID-19. IMSS. Published by Elsevier Inc. 2020-07 2020-04-15 /pmc/articles/PMC7158763/ /pubmed/32327293 http://dx.doi.org/10.1016/j.arcmed.2020.04.006 Text en © 2020 IMSS. Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Ghaffari, Samad
Roshanravan, Neda
Tutunchi, Helda
Ostadrahimi, Alireza
Pouraghaei, Mahboub
Kafil, Behnam
Oleoylethanolamide, A Bioactive Lipid Amide, as A Promising Treatment Strategy for Coronavirus/COVID-19
title Oleoylethanolamide, A Bioactive Lipid Amide, as A Promising Treatment Strategy for Coronavirus/COVID-19
title_full Oleoylethanolamide, A Bioactive Lipid Amide, as A Promising Treatment Strategy for Coronavirus/COVID-19
title_fullStr Oleoylethanolamide, A Bioactive Lipid Amide, as A Promising Treatment Strategy for Coronavirus/COVID-19
title_full_unstemmed Oleoylethanolamide, A Bioactive Lipid Amide, as A Promising Treatment Strategy for Coronavirus/COVID-19
title_short Oleoylethanolamide, A Bioactive Lipid Amide, as A Promising Treatment Strategy for Coronavirus/COVID-19
title_sort oleoylethanolamide, a bioactive lipid amide, as a promising treatment strategy for coronavirus/covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158763/
https://www.ncbi.nlm.nih.gov/pubmed/32327293
http://dx.doi.org/10.1016/j.arcmed.2020.04.006
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