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Assessment of putative protein targets derived from the SARS genome

The ability to rapidly and reliably develop hypotheses on the function of newly discovered protein sequences requires systematic and comprehensive analysis. Such an analysis, embodied within the DS GeneAtlas™ pipeline, has been used to critically evaluate the severe acute respiratory syndrome (SARS)...

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Detalles Bibliográficos
Autores principales: Yan, Lisa, Velikanov, Mikhail, Flook, Paul, Zheng, Wenjin, Szalma, Sándor, Kahn, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159027/
https://www.ncbi.nlm.nih.gov/pubmed/14623076
http://dx.doi.org/10.1016/S0014-5793(03)01115-3
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author Yan, Lisa
Velikanov, Mikhail
Flook, Paul
Zheng, Wenjin
Szalma, Sándor
Kahn, Scott
author_facet Yan, Lisa
Velikanov, Mikhail
Flook, Paul
Zheng, Wenjin
Szalma, Sándor
Kahn, Scott
author_sort Yan, Lisa
collection PubMed
description The ability to rapidly and reliably develop hypotheses on the function of newly discovered protein sequences requires systematic and comprehensive analysis. Such an analysis, embodied within the DS GeneAtlas™ pipeline, has been used to critically evaluate the severe acute respiratory syndrome (SARS) genome with the goal of identifying new potential targets for viral therapeutic intervention. This paper discusses several new functional hypotheses on the roles played by the constituent gene products of SARS, and will serve as an example of how such assignments can be developed or extended on other systems of interest.
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spelling pubmed-71590272020-04-15 Assessment of putative protein targets derived from the SARS genome Yan, Lisa Velikanov, Mikhail Flook, Paul Zheng, Wenjin Szalma, Sándor Kahn, Scott FEBS Lett Full‐length Articles The ability to rapidly and reliably develop hypotheses on the function of newly discovered protein sequences requires systematic and comprehensive analysis. Such an analysis, embodied within the DS GeneAtlas™ pipeline, has been used to critically evaluate the severe acute respiratory syndrome (SARS) genome with the goal of identifying new potential targets for viral therapeutic intervention. This paper discusses several new functional hypotheses on the roles played by the constituent gene products of SARS, and will serve as an example of how such assignments can be developed or extended on other systems of interest. John Wiley and Sons Inc. 2003-11-20 2003-10-24 /pmc/articles/PMC7159027/ /pubmed/14623076 http://dx.doi.org/10.1016/S0014-5793(03)01115-3 Text en FEBS Letters 554 (2003) 1873-3468 © 2015 Federation of European Biochemical Societies This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.
spellingShingle Full‐length Articles
Yan, Lisa
Velikanov, Mikhail
Flook, Paul
Zheng, Wenjin
Szalma, Sándor
Kahn, Scott
Assessment of putative protein targets derived from the SARS genome
title Assessment of putative protein targets derived from the SARS genome
title_full Assessment of putative protein targets derived from the SARS genome
title_fullStr Assessment of putative protein targets derived from the SARS genome
title_full_unstemmed Assessment of putative protein targets derived from the SARS genome
title_short Assessment of putative protein targets derived from the SARS genome
title_sort assessment of putative protein targets derived from the sars genome
topic Full‐length Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159027/
https://www.ncbi.nlm.nih.gov/pubmed/14623076
http://dx.doi.org/10.1016/S0014-5793(03)01115-3
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